Concentrations of oocyte secreted GDF9 and BMP15 decrease with MII transition during human IVM.
Jesús CadenasSusanne Elisabeth PorsAjay KumarBhanu KalraStine Gry KristensenClaus Yding AndersenLinn Salto MamsenPublished in: Reproductive biology and endocrinology : RB&E (2022)
These data suggest that the driving mechanisms for oocyte nuclear maturation may involve both GDF9 and BMP15 homodimers, while the role of the GDF9/BMP15 heterodimer is questionable.