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Serum neurofilament levels correlate with electrodiagnostic evidence of axonal loss in paclitaxel-induced peripheral neurotoxicity.

Roser VelascoA A ArgyriouC MarcoS MariottoA StradellaJ HernándezS PernasS FerrariJ Bruna
Published in: Journal of neurology (2022)
sNfL levels proportionally increase during chemotherapy administration and significantly correlate with NCS axonal abnormalities in patients with PIPN. A multimodal testing approach employing both sNfL and NCS might improve the PIPN diagnostic accuracy.
Keyphrases
  • spinal cord injury
  • chemotherapy induced
  • diabetic rats
  • cerebrospinal fluid
  • squamous cell carcinoma
  • optic nerve
  • oxidative stress
  • radiation therapy
  • chronic pain