Serum neurofilament levels correlate with electrodiagnostic evidence of axonal loss in paclitaxel-induced peripheral neurotoxicity.
Roser VelascoA A ArgyriouC MarcoS MariottoA StradellaJ HernándezS PernasS FerrariJ BrunaPublished in: Journal of neurology (2022)
sNfL levels proportionally increase during chemotherapy administration and significantly correlate with NCS axonal abnormalities in patients with PIPN. A multimodal testing approach employing both sNfL and NCS might improve the PIPN diagnostic accuracy.