Pediatric Features of Genetic Predisposition to Polycystic Ovary Syndrome.

Jia ZhuAnders U EliasenIzzuddin M ArisSara Elizabeth StinsonJens-Christian HolmTorben Hansen Marie-France HivertKlaus BønnelykkeRany M SalemJoel N HirschhornYee-Ming Chan

Published in: The Journal of clinical endocrinology and metabolism (2023)

Genetic risk factors for PCOS are associated with alterations in metabolic and growth and developmental traits in childhood. Thus, PCOS may not simply be a condition that affects reproductive-age women but, rather, one possible manifestation of an underlying condition that affects both sexes starting in early life.

Keyphrases

polycystic ovary syndrome
early life
genome wide
insulin resistance
copy number
dna methylation
adipose tissue
metabolic syndrome
type diabetes
gene expression
young adults