Combination of computed tomography angiography with coronary artery calcium score for improved diagnosis of coronary artery disease: a collaborative meta-analysis of stable chest pain patients referred for invasive coronary angiography.
Mahmoud MohamedMaria BosserdtViktoria WieskeBenjamin DubourgHatem AlkadhiMario J GarciaSebastian LeschkaElke ZimmermannAbbas A ShabestariBjarne L NørgaardMatthijs F L MeijsKristian A ØvrehusAxel C P DiederichsenJuhani KnuutiBjørn A HalvorsenVladymir Mendoza-RodriguezYung-Liang WanNuno BettencourtEugenio MartuscelliRonny R BuechelHans MickleyKai SunSimone MuragliaPhilipp A KaufmannBernhard A HerzogJean-Claude TardifGeorg M SchützMichael LauleDavid E NewbyStephan AchenbachMatthew BudoffRobert HaaseFederico BiavatiAldo Vásquez MézquitaPeter SchlattmannMarc Deweynull nullPublished in: European radiology (2023)
• The combination of coronary artery calcium with coronary computed tomography angiography showed significantly higher AUC (87%, 95% confidence interval [CI]: 86 to 89%) for diagnosis of coronary artery disease compared to coronary computed tomography angiography alone (80%, 95% CI: 78 to 82%, p < 0.001). • Diagnostic improvement was mostly seen in patients with non-diagnostic C. • The improvement in diagnostic performance and the net benefit was consistent across age groups, chest pain types, and genders.
Keyphrases
- coronary artery
- coronary artery disease
- pulmonary artery
- systematic review
- end stage renal disease
- percutaneous coronary intervention
- ejection fraction
- newly diagnosed
- chronic kidney disease
- prognostic factors
- type diabetes
- peritoneal dialysis
- magnetic resonance imaging
- heart failure
- magnetic resonance
- computed tomography
- acute coronary syndrome
- atrial fibrillation
- patient reported outcomes
- transcatheter aortic valve replacement