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Assessment of association between lipoxygenase genes variants in elderly Greek population and type 2 diabetes mellitus.

Xanthippi A TsekmekidouKalliopi D KotsaFotis S TsetsosTriantafyllos P DidangelosMarianthi A GeorgitsiAthanasios K RoumeliotisStylianos A PanagoutsosElias D ThodisMarios T TheodoridisNikolaos P PapanasDimitrios A PapazoglouPloumis S PasadakisMaltezos S EustratiosPeristera I PaschouJohn G Yovos
Published in: Diabetes & vascular disease research (2018)
These results indicate a potential protective role of ALOX5AP and 5-arachidonate lipoxygenase gene in diabetes pathogenesis, indicating further the importance of the relationship between diabetes and inflammation. Larger population studies are required to replicate our findings.
Keyphrases
  • glycemic control
  • type diabetes
  • cardiovascular disease
  • copy number
  • genome wide
  • oxidative stress
  • middle aged
  • metabolic syndrome
  • weight loss
  • genome wide analysis
  • skeletal muscle
  • human health