Is impaired lung function related to spinal deformities in patients with adolescent idiopathic scoliosis? A systematic review and meta-analysis-SOSORT 2019 award paper.

Mandy Ming Pui Kan Stefano Negrini Francesca Di Felice Prudence Wing Hang Cheung Sabrina Donzelli Fabio Zaina Dino Samartzis Esther T C Cheung Arnold Yu Lok Wong

Published in: European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society (2022)

Larger thoracic Cobb angles, greater apical vertebral rotation angle, or hypokyphosis were significantly associated with greater pulmonary impairments in patients with AIS, although the evidence was limited. From a clinical perspective, the results highlight the importance of minimizing the three-dimensional spinal deformity in preserving lung function in these patients. More research is warranted to confirm these results.

Keyphrases

lung function
cystic fibrosis
chronic obstructive pulmonary disease
air pollution
spinal cord
end stage renal disease
ejection fraction
newly diagnosed
high resolution
pulmonary hypertension
prognostic factors
peritoneal dialysis
patient reported outcomes
mass spectrometry