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Association between occupational exposure to irritant agents and a distinct asthma endotype in adults.

Miora Valérie AndrianjafimasyMickaël FebrissyFarid ZerimechBrigitte DananchéHans J KromhoutRégis MatranMohamed NadifDominique Oberson-GenesteCatherine QuinotVivi SchlünssenValérie SirouxJan-Paul ZockNicole Le MoualRachel NadifOrianne Dumas
Published in: Occupational and environmental medicine (2021)
Occupational exposure to irritants was associated with a distinct respiratory endotype suggesting oxidative stress and neutrophilic inflammation as potential associated biological mechanisms.
Keyphrases
  • oxidative stress
  • chronic obstructive pulmonary disease
  • dna damage
  • diabetic rats
  • ischemia reperfusion injury
  • induced apoptosis
  • heat shock
  • climate change
  • heat shock protein