Tacrolimus Impairs Kupffer Cell Capacity to Control Bacteremia: Why Transplant Recipients Are Susceptible to Infection.

Carsten DeppermannMoritz PeiselerJoel ZindelLori ZbytnuikWoo-Yong LeeElisa PasiniCristina BaciuJohn MatelskiYun LeeDeepali KumarAtul HumarBas SurewaardPaul KubesMamatha Bhat

Published in: Hepatology (Baltimore, Md.) (2021)

Our results indicate that tacrolimus treatment has a significant impact directly on KCs and on TREM1, thereby compromising their capacity to fend off infections.

Keyphrases

single cell
cell therapy
stem cells
mesenchymal stem cells
combination therapy
multidrug resistant