External beam radiation therapy improves survival in low-volume metastatic prostate cancer patients: a North American population-based study.
Lara Franziska StolzenbachMarina DeukerClaudia Collà RuvoloLuigi NoceraMila MansourZhe TianDerya TilkiThomas SteuberAlberto BrigantiFred SaadFelix K H ChunMarkus GraefenPierre I KarakiewiczPublished in: Prostate cancer and prostatic diseases (2020)
We validated the OM reduction associated with EBRT in M1a and M1b patients with PSA ≤ 10.0 ng/ml but not in M1b patients with PSA > 10.0 ng/ml. In consequence, it appears that a smaller subset of North American mPCa patients benefit of EBRT than originally reported in European patients. Further North American validation studies are essential.