Circulating transthyretin and retinol binding protein 4 levels among middle-age V122I TTR carriers in the general population.
Nicholas S HendrenJames A De LemosJarett D BerryJulia KozlitinaLorena SaelicesAlan X JiZhili ShaoChia-Feng LiuSonia GargMaryjane A FarrMark H DraznerW H Wilson TangJustin L GrodinPublished in: Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis (2024)
V122I TTR carrier status is independently associated with lower TTR and RBP4 in comparison with non-carriers. These findings support the hypothesis that TTR and RBP4 may correlate with evidence of subclinical ATTRv-CA.
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