Astilbe Chinensis ethanol extract suppresses inflammation in macrophages via NF-κB pathway.

Tae-Young GilBo-Ram JinChul-Hee HongJong Hyuk ParkHyo-Jin An

Published in: BMC complementary medicine and therapies (2020)

Our findings manifested that ACE inhibited LPS or TG-induced inflammation by blocking the NF-κB signaling pathway in macrophages. It indicated that ACE is a potential therapeutic mean for inflammation and related diseases.

Keyphrases

signaling pathway
oxidative stress
diabetic rats
pi k akt
induced apoptosis
lps induced
epithelial mesenchymal transition
angiotensin ii
angiotensin converting enzyme
inflammatory response
anti inflammatory
drug induced
high glucose
immune response