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Management and Outcome of COVID-19 Infection Using Nirmatrelvir/Ritonavir in Kidney Transplant Patients.

Pierre GiguèreMarie-Josée DeschenesMacKenzie Van LoonStephanie HoarTodd FairheadRinu PazhekattuGreg A KnollJolanta KarpinskiNamrata ParikhJessica McDougallMichaeline McGuintySwapnil S Hiremath
Published in: Clinical journal of the American Society of Nephrology : CJASN (2023)
Withholding tacrolimus starting the day before initiation of nirmatrelvir/ritonavir with resumption 3 days after completion of therapy resulted in a low incidence of supratherapeutic levels but a short period of subtherapeutic levels for many patients. AKI was infrequent. The data are limited by the small sample size and short follow-up.
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