The mutational landscape of cancer's vulnerability to ionizing radiation.

Priyanka Gopal Brian D Yard Aaron Petty Jessica C Lal Titas K Bera Trung Q Hoang Alexandru D Buhimschi Mohamed E Abazeed

Published in: Clinical cancer research : an official journal of the American Association for Cancer Research (2022)

Our results reveal new insights into the genetic determinants of tumor sensitivity to radiotherapy and nominate a multitude of cancer mutations that are predicted to impact treatment efficacy.

Keyphrases

papillary thyroid
squamous cell
genome wide
early stage
climate change
single cell
dna methylation
squamous cell carcinoma
locally advanced
radiation induced
childhood cancer
copy number
combination therapy