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Effect of a single dose of zoledronic acid on bone mineral density and trabecular bone score in Indian postmenopausal osteoporotic women with and without type 2 diabetes mellitus - A prospective cohort pilot study.

Chandhana MeruguJaya Prakash SahooSadishkumar KamalanathanGovindarajalou RamkumarSagili Vijaya Bhaskar ReddySitanshu Sekhar KarDukhabandhu NaikAyan RoyNiya NarayananDeepika PatelVarun Suryadevara
Published in: Endocrine (2023)
The gain in the LS-BMD was significantly lower in T2DM group compared to non-DM subjects over 12 months after a single IV infusion of 4 mg ZA. The explanation for this could be low bone turnover in diabetes subjects at baseline.
Keyphrases
  • bone mineral density
  • glycemic control
  • postmenopausal women
  • body composition
  • type diabetes
  • cardiovascular disease
  • low dose
  • weight loss
  • insulin resistance
  • adipose tissue
  • cardiovascular risk factors