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Influence of single nucleotide polymorphisms among cigarette smoking and non-smoking patients with coronary artery disease, urinary bladder cancer and lung cancer.

Nongnit L LewinJan-Erik KarlssonDavid L RobinsonMatida FagerbergMagnus KentssonShariel SayardoustMats NilssonLevar ShamounBengt-Åke AnderssonSture LöfgrenLars Erik RutqvistFreddi Lewin
Published in: PloS one (2021)
SNPs might be important risk factors for CAD, UBCa and LCa. Distribution of the SNPs was specific for each patient group, not a random event. Impact of cigarette smoking on the disease was associated to the specific SNP sequences. Thus, smoking individuals with SNPs associated to risk of these serious diseases is an important target group for smoking cessation programs.
Keyphrases
  • smoking cessation
  • genome wide
  • replacement therapy
  • dna methylation
  • genome wide association
  • coronary artery disease
  • public health
  • case report
  • high density