Association of genetic polymorphisms in VEGF -460, -7 and -583 and hematocrit level with the development of idiopathic recurrent pregnancy loss and a meta-analysis.

Yong-Wook JungEun Hee AhnJung Oh KimHui Jeong AnSung Hwan ChoYoung Ran KimWoo Sik LeeNam Keun Kim

Published in: The journal of gene medicine (2018)

The VEGF rs833061/rs3025020 genotype allele was related to the development of RPL and was also associated with maternal blood HCT levels in RPL patients. However, further studies are needed to clarify the exact mechanism of how VEGF and HCT are involved in RPL development.

Keyphrases

vascular endothelial growth factor
endothelial cells
ejection fraction
newly diagnosed
pregnancy outcomes
patient reported outcomes
cell cycle arrest
cell proliferation
signaling pathway
case control