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Proteomics identifies differentially expressed proteins in glioblastoma U87 cells treated with hederagenin.

Yesen ZhangYi HanYuchun ShangXiangyu WangJiwei Sun
Published in: Proteome science (2023)
Hederagenin inhibition of GBM U87 cells may be related to KIF7, which is mainly involved in the hedgehog signaling pathway. Our findings lay a foundation for additional study of the therapeutic mechanism of hederagenin.
Keyphrases
  • induced apoptosis
  • signaling pathway
  • cell cycle arrest
  • endoplasmic reticulum stress
  • pi k akt
  • epithelial mesenchymal transition
  • oxidative stress
  • genome wide
  • dna methylation
  • drug induced