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Proper evaluation of chemical cross-linking-based spatial restraints improves the precision of modeling homo-oligomeric protein complexes.

Aljaž GaberGregor GunčarMiha Pavšič
Published in: BMC bioinformatics (2019)
Our findings provide guidelines for proper evaluation of chemical cross-linking-based spatial restraints in modeling homo-oligomeric protein complexes, which could facilitate structural characterization of this important group of proteins.
Keyphrases
  • protein protein
  • amino acid
  • binding protein
  • clinical practice