Evaluation of polygenic risk scores for ovarian cancer risk prediction in a prospective cohort study.

Xin YangGoska LeslieAleksandra Gentry-MaharajAndy RyanMaria IntermaggioAndrew LeeJatinderpal K KalsiJonathan TyrerFaiza GabaRanjit ManchandaPaul D P PharoahSimon A GaytherSusan J RamusIan JacobsUsha MenonAntonis C Antoniou

Published in: Journal of medical genetics (2018)

PRSs can be used to predict future risk of developing ovarian cancer for women in the general population. Incorporation of PRSs into risk prediction models for EOC could inform clinical decision-making and health management.

Keyphrases

decision making
healthcare
public health
polycystic ovary syndrome
mental health
current status
health information
breast cancer risk
pregnancy outcomes
type diabetes
risk assessment
metabolic syndrome
human health
climate change
cervical cancer screening