Involvement of ABC-transporters and acyltransferase 1 in intracellular cholesterol-mediated autophagy in bovine alveolar macrophages in response to the Bacillus Calmette-Guerin (BCG) infection.

Jinrui XuYanbing ZhouYi YangCuiping LvXiao-Ming LiuYujiong Wang

Published in: BMC immunology (2020)

This study thus provides an insight into into a mechanism by which the cholesterol metabolism regulated the autophagy in macrophages in response to mycobacterial infections.

Keyphrases

cell death
endoplasmic reticulum stress
low density lipoprotein
signaling pathway
oxidative stress
mycobacterium tuberculosis
transcription factor
reactive oxygen species
bacillus subtilis