Characterization of APOBEC3 variation in a population of HIV-1 infected individuals in northern South Africa.

Nontokozo D MatumeDenis M TebitLaurie R GrayStephen D TurnerDavid RekoshPascal O BessongMarie-Louise Hammarskjöld

Published in: BMC medical genetics (2019)

The study showed significant polymorphisms in the APOBEC3D, 3F, 3G and 3H genes in our South African HIV1-infected cohort. In the case of all of these genes, the polymorphisms were generally present at higher frequencies than reported in other 1000 genome populations and in the ExAC exome consortium database .

Keyphrases

hiv infected
antiretroviral therapy
genome wide
south africa
hiv positive
human immunodeficiency virus
genome wide identification
copy number
dna methylation
adverse drug