Bio-Heat Model of Kilohertz-Frequency Deep Brain Stimulation Increases Brain Tissue Temperature.
Niranjan KhadkaIrene E HarmsenAndres M LozanoMarom BiksonPublished in: Neuromodulation : journal of the International Neuromodulation Society (2020)
Subject to validation with in vivo measurements, neuromodulation through a heating mechanism of action by 10 kHz-DBS can indicate novel therapeutic pathways and strategies for dose optimization.