Shared Genetic Etiology of Obesity-Related Traits and Barrett's Esophagus/Adenocarcinoma: Insights from Genome-Wide Association Studies.
Anne C BöhmerJulian HeckerJulia SchröderPuya GharahkhaniAndrea MayChristian GergesMario AndersJessica BeckerTimo HessNicole KreuserRené ThiemeTania NoderMarino VeneritoLothar VeitsThomas SchmidtClaudia FuchsJakob R IzbickiArnulf H HölscherArne DietrichYusef MoullaOrestis LyrosHauke LangDietmar LorenzBrigitte SchumacherRupert MayershoferYogesh VashistKatja OttMichael ViethJosef WeismüllerSusanne MoebusMichael KnappHorst NeuhausThomas RöschChristian EllMarkus M NöthenDavid C WhitemanIan TomlinsonJanusz JankowskiRebecca C FitzgeraldClaire PallesThomas L VaughanInes GockelAaron P ThriftHeide FierJohannes SchumacherPublished in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology (2019)
Our study quantifies the genetic correlation between BE/EA and obesity. Further research is now warranted to elucidate these effects and to understand the shared pathophysiology.