Integrated analysis of lncRNA and mRNA expression profiles in patients with unexplained recurrent spontaneous abortion.
Xiaoli ZhuMengxuan DuHeng GuRuishan WuMengge GaoHang XuJia TangMingzhen LiXiaohua LiuXingming ZhongPublished in: American journal of reproductive immunology (New York, N.Y. : 1989) (2023)
We identified seven top hub genes, constructed a lncRNA-related network and suggested that IGF1 plays a key role in regulating maternal immune response by affecting NK and T cells' function, which helps to identify the pathogenesis of URSA. This article is protected by copyright. All rights reserved.
Keyphrases
- immune response
- bioinformatics analysis
- long non coding rna
- long noncoding rna
- network analysis
- wastewater treatment
- genome wide
- birth weight
- pregnancy outcomes
- toll like receptor
- pi k akt
- genome wide identification
- cell proliferation
- dna methylation
- physical activity
- pregnant women
- transcription factor
- drug induced
- preterm birth