Alterations in epidermal stem cells within the pilosebaceous unit in atrophic acne scars.

Dong Hyo KimJi Young YoonJun Hyo LeeDae Hun Suh

Published in: The Australasian journal of dermatology (2024)

These findings suggest that as inflammatory acne lesions progress, inflammation gradually infiltrates the pilosebaceous unit and affects the resident stem cells. This disruption impedes the normal regeneration of the interfollicular epidermis and adnexal structures, resulting in atrophic acne scars.

Keyphrases

stem cells
hidradenitis suppurativa
oxidative stress
platelet rich plasma
cell therapy
patient safety
quality improvement
high resolution
wound healing
bone marrow