Extensive acute and sustained changes to neutrophil proteomes post-SARS-CoV-2 infection.

Merete B LongAndrew Jm HowdenHolly R KeirChristina M RollingsYan Hui GiamThomas PembridgeLilia DelgadoHani Abo-LeyahAmy F LloydGabriel SollbergerRebecca HullAmy GilmourChloe HughesBenjamin Jm NewDiane CassidyAmelia ShoemarkHollian RichardsonAngus I LamondDoreen A CantrellJames D ChalmersAlejandro J Brenes

Published in: The European respiratory journal (2023)

SARS-CoV-2 infection results in the sustained presence of circulating neutrophils with distinct proteomes suggesting altered metabolic and immunosuppressive profiles and altered capacities to respond to migratory signals and cues from other immune cells, pathogens or cytokines.

Keyphrases

respiratory syndrome coronavirus
liver failure
respiratory failure
gram negative
aortic dissection
drug induced
sars cov
antimicrobial resistance
coronavirus disease
multidrug resistant
hepatitis b virus