Intestinal microbiomics and hepatic metabolomics insights into the potential mechanisms of probiotic Bifidobacterium pseudolongum CCFM1253 prevents the acute liver injury in mice.
Weiling GuoShumao CuiXin TangYongqiu YanFeifei XiongQiuxiang ZhangJianxin ZhaoBingyong MaoHao ZhangPublished in: Journal of the science of food and agriculture (2023)
B. pseudolongum CCFM1253 can effectively alleviate inflammatory response and oxidative stress, and regulate the intestinal microbiota composition and liver metabolism, and elevate the liver riboflavin content in LPS-treated mice. Therefore, B. pseudolongum CCFM1253 could serves as a potential probiotic to ameliorate the host health. This article is protected by copyright. All rights reserved.
Keyphrases
- liver injury
- drug induced
- inflammatory response
- oxidative stress
- high fat diet induced
- human health
- public health
- healthcare
- bacillus subtilis
- lipopolysaccharide induced
- liver failure
- dna damage
- mass spectrometry
- mental health
- toll like receptor
- respiratory failure
- metabolic syndrome
- insulin resistance
- type diabetes
- immune response
- intensive care unit
- induced apoptosis
- extracorporeal membrane oxygenation
- skeletal muscle