Radiotherapy plus temozolomide with or without anlotinib in H3K27M-mutant diffuse midline glioma: A retrospective cohort study.

Chao LiuShuwen KuangTianxiang HuangJun WuLongbo ZhangXuan Gong

Published in: CNS neuroscience & therapeutics (2024)

This study first reported that anlotinib combined with Stupp regimen is a safe and feasible regimen for newly diagnosed patients with H3K27M-DMG. Further, anlotinib showed significant efficacy for H3K27M-DMG located in the infratentorial region.

Keyphrases

newly diagnosed
early stage
radiation therapy
low grade
locally advanced
squamous cell carcinoma
radiation induced