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Integrating rapamycin with novel PI3K/Akt/mTOR inhibitor microRNAs on NOTCH1-driven T-cell acute lymphoblastic leukemia (T-ALL).

Fateme ArjmandSamaneh ShojaeiMitra KhaliliHossein DinmohammadiBehzad PoopakSamira Mohammadi-YeganehYousef Mortazavi
Published in: BioImpacts : BI (2023)
These preliminary results highlight the potential for improving T-ALL treatment through multi-targeted therapeutic strategies involving rapamycin and miR-3143/miR-3182.
Keyphrases
  • cell proliferation
  • acute lymphoblastic leukemia
  • long non coding rna
  • long noncoding rna
  • cancer therapy
  • drug delivery
  • combination therapy