Factors influencing survival among patients with HER2-positive metastatic breast cancer treated with trastuzumab.
Phillip S BlanchetteD N DesautelsG R PondJ M S BartlettS Nofech-MozesM J YaffeK I PritchardPublished in: Breast cancer research and treatment (2018)
Older age, increased PLR, and ALP were identified as poor prognostic factors and ER positivity as a favorable prognostic factor for OS after adjusting for the presence of CNS metastasis and the presence of number of ≥ 2 distant metastatic sites. Increased PLR was a poor prognostic factor for both OS and FFS, and warrants further investigation into its prognostic ability amongst patients with HER2-positive metastatic breast cancer.