[Metabolic, inflammatory and imaging biomarkers in evaluation of coronary atherosclerosis severity in patients with coronary artery disease and diabetes mellitus type 2].
O A KoshelskayaO A KharitonovaIrina V KologrivovaT E SuslovaNatalya Yu MargolisE K TereshenkovaA N RybinaR S KarpovPublished in: Terapevticheskii arkhiv (2021)
Study results demonstrate differences in mechanisms of deposition and functioning of epicardial and abdominal adipose tissue depending on the presence or absence of diabetic status. Patients with DM2 are characterized by the excessive EAT deposition and decrease of serum adiponectin levels compared to non-diabetic patients in the equal conditions. Independent markers of CAD severity in DM 2 are decreased HDL-C and increased hsCRP levels, but not EATt.
Keyphrases
- adipose tissue
- coronary artery disease
- insulin resistance
- glycemic control
- type diabetes
- high resolution
- coronary artery
- metabolic syndrome
- cardiovascular disease
- oxidative stress
- high fat diet
- weight gain
- heart failure
- body mass index
- wound healing
- mass spectrometry
- photodynamic therapy
- aortic valve
- transcatheter aortic valve replacement