Systematic Review of Aortic Dissection Detection Risk Score Plus D-dimer for Diagnostic Rule-out Of Suspected Acute Aortic Syndromes.

Paolo BimaEmanuele PivettaPeiman NazerianMamoru ToyofukuRiccardo GorlaEduardo BossoneRaimund ErbelEnrico LupiaFulvio Morello

Published in: Academic emergency medicine : official journal of the Society for Academic Emergency Medicine (2020)

Despite methodologic limitations, integration of ADD-RS = 0 or ≤ 1 with DD < 500 ng/mL shows negligible heterogeneity and consistently high sensitivity across studies, thus supporting reliability for diagnostic rule-out of AASs. Data supporting ADD-RS = 0 plus DDage-adj appear preliminary and require further scrutiny.

Keyphrases

aortic dissection
systematic review
meta analyses
single cell
pulmonary embolism
electronic health record
big data
loop mediated isothermal amplification
heart failure
case control
liver failure
machine learning
deep learning
atrial fibrillation