Nonalcoholic fatty liver disease and eGFR levels could be linked by the PNPLA3 I148M polymorphism in children with obesity.
Pierluigi MarzuilloAnna Di SessaStefano GuarinoDaniela CapalboGiuseppina Rosaria UmanoMarcella PedullàAngela La MannaGrazia CirilloEmanuele Miraglia Del GiudicePublished in: Pediatric obesity (2019)
Children with obesity and PNPLA3 MM genotype show lower eGFR levels compared with other genotypes, with a major effect of this polymorphism in the presence of NAFLD.