Pregnancy in Charcot-Marie-Tooth disease: Data from the Italian CMT national registry.
Chiara PisciottaDaniela CalabreseLucio SantoroIrene TramacereFiore ManganelliGian Maria FabriziAngelo SchenoneTiziana CavallaroMarina GrandisStefano C PrevitaliIsabella AllegriLuca PaduaCostanza PazzagliaPaola SaveriAldo QuattronePaola ValentinoStefano TozzaLuca GentileMassimo RussoAnna MazzeoMaria Claudia TrapassoFabio ParazziniGiuseppe VitaDavide Pareysonnull nullPublished in: Neurology (2020)
We observed higher rates of placenta previa, abnormal presentations, and preterm deliveries in CMT, but pregnancy outcome and newborn weight and health were similar to those of the reference populations. Worsening of CMT is not infrequent and occurs not only in CMT1A. Pregnant women with CMT should be monitored with particular care.