Anticoagulation strategy for patients presenting with ischemic strokes while using a direct oral anticoagulant: a systematic review and meta-analysis.

João Paulo Motta TellesGiulia Isadora CenciGabriel Marinheiro Dos Santos BezerraGabriela Borges NagerRebeka Bustamante RochaFernanda Ferreira BomtempoEberval Gadelha FigueiredoGisele Sampaio Silva

Published in: International journal of stroke : official journal of the International Stroke Society (2024)

Post-stroke adjustments to anticoagulation therapy-whether altering the drug or its dosage-do not yield additional benefits. Additionally, the results suggest that warfarin may be less effective than DOACs for preventing stroke recurrence, bleeding complications, and death in this patient population.

Keyphrases

atrial fibrillation
direct oral anticoagulants
oral anticoagulants
venous thromboembolism
case report
risk factors
ischemia reperfusion injury
emergency department
stem cells
cerebral ischemia
drug induced
brain injury
cell therapy
replacement therapy