Clinical description and outcome of overall varicella-zoster virus-related organ dysfunctions admitted in intensive care units: the VAZOREA cohort study.

Jolan MalherbePierre GodardJean-Claude LacheradeValentin CoirierLaurent ArgaudHervé HyvernatFrancis SchneiderJulien CharpentierFlorent WalletJuliette PocquetGaëtan PlantefeveJean-Pierre QuenotPierre BayAgathe DelboveHugues GeorgesTomas UrbinaDavid SchnellCharlène Le MoalMatthieu StanowskiCorentin MurisMaud JonasBertrand SauneufOlivier LesieurAmaury LhermitteLaure CalvetInes GueguenDamien du Cheyron

Published in: Annals of intensive care (2024)

Overall, severe VZV manifestations are associated with high mortality in the ICU, which appears to be driven by immunosuppression status rather than any specific organ involvement. Deciphering the clinical phenotypes may help clinicians identify high-risk patients and assess prognosis.

Keyphrases

intensive care unit
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
prognostic factors
mechanical ventilation
cardiovascular events
type diabetes
early onset
extracorporeal membrane oxygenation