Systemic arterial blood pressure determines the therapeutic window of non-selective beta blockers in decompensated cirrhosis.
Tammo L TergastMarkus KimmannHans LaserSvetlana GerbelMichael P MannsMarkus CornbergBenjamin MaasoumyPublished in: Alimentary pharmacology & therapeutics (2019)
Ascites, acute-on-chronic liver failure and spontaneous bacterial peritonitis do not limit the safe use of non-selective β-blockers in patients with cirrhosis. Mean arterial blood pressure might represent a better indicator to determine the therapeutic window of non-selective β-blocker treatment.