Serum neurofilament light concentrations are associated with cortical thinning in anorexia nervosa.
Inger HellerhoffFabio BernardoniKlaas BahnsenJoseph A KingArne DooseSophie PauligkFriederike I TamMerle MannigelKatrin GramatkeVeit RoessnerKatja AkgünTjalf ZiemssenStefan EhrlichPublished in: Psychological medicine (2023)
A speculative interpretation would be that cortical thinning in acute AN might be at least partially a result of axonal damage processes. Further studies should thus test the potential of serum NF-L to become a reliable, low-cost and minimally invasive marker of structural brain alterations in AN.