Identifying the association between serum urate levels and gout flares in patients taking urate-lowering therapy: a post hoc cohort analysis of the CARES trial with consideration of dropout.

Sara K TedeschiKeigo HayashiYuqing ZhangHyon ChoiDaniel H Solomon

Published in: Annals of the rheumatic diseases (2024)

Gout flare rates were persistently higher when SU ≥6 mg/dL after the first year of ULT after accounting for censoring. The spike in flares in all categories after stopping prophylaxis suggests a longer duration of prophylaxis may be warranted.

Keyphrases

end stage renal disease
newly diagnosed
uric acid
chronic kidney disease
prognostic factors
study protocol
stem cells
metabolic syndrome
mesenchymal stem cells
bone marrow
patient reported
open label