Antifungal resistance on Sporothrix species: an overview.
Stefanie Bressan WallerDaiane Flores Dalla LanaPriscilla Maciel QuatrinMarcos Roberto Alves FerreiraAlexandre Meneghello FuentefriaAdelina MezzariPublished in: Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] (2020)
The emergence of Sporothrix species with in vitro antifungal resistance was evidenced and the possible mechanisms for resistance development may be due to the melanin production capacity, genetic diversity and mutations in cytochrome P450. Further studies should be carried out targeting gene expression for the development of antifungal resistance on Sporothrix species in order to prospect new therapeutic targets for human and veterinary use.