Login / Signup

GIPC3 couples to MYO6 and PDZ domain proteins and shapes the hair cell apical region.

Paroma ChatterjeeClive P MorganJocelyn F KreyConnor BensonJennifer GoldsmithMichael BateschellAnthony J RicciPeter G Barr-Gillespie
Published in: bioRxiv : the preprint server for biology (2023)
The PDZ-domain protein GIPC3 couples the molecular motors MYO6 and MYO18A to actin cytoskeleton structures in hair cells. GIPC3 is necessary for shaping the hair cell’s cuticular plate and hence the arrangement of the stereocilia in the hair bundle.
Keyphrases
  • single cell
  • cell therapy
  • induced apoptosis
  • stem cells
  • cell cycle arrest
  • intimate partner violence
  • mesenchymal stem cells
  • bone marrow
  • cell proliferation
  • signaling pathway
  • pi k akt