Severe methyl bromide poisoning causing early acute renal failure and anuria: a case report.
Yaqian LiGuangcai YuLongke ShiLiwen ZhaoZixin WenBaotian KanWenjun WangXiangdong JianPublished in: The Journal of international medical research (2022)
Methyl bromide is a pre-plant soil fumigant that is widely used to control nematodes, insects, and fungi in farmlands. Methyl bromide enters the human body through dermal absorption or inhalation and can damage the respiratory, nervous, circulatory, urinary, and other systems. A 62-year-old man who had inhaled a large amount of methyl bromide was admitted to our department. He presented with respiratory failure and pink foamy sputum. He was started on dexamethasone, alanyl glutamine, sulbactam, furosemide, vitamin B 1 , mouse nerve growth factor, and other treatments, and mechanical ventilation and continuous venovenous hemodiafiltration (CVVHF) were performed daily. He subsequently developed coagulopathy because of the CVVHF, for which protamine, recombinant human brain natriuretic peptide, and albumin were administered intravenously. Notably, the patient developed sustained anuria and eventually died owing to multiple organ failure; specifically, failure of the brain, heart, lungs, and kidneys. This report presents the diagnosis, clinical course, management, and prognosis of a patient who was treated at our hospital for severe methyl bromide poisoning.
Keyphrases
- respiratory failure
- mechanical ventilation
- extracorporeal membrane oxygenation
- growth factor
- acute respiratory distress syndrome
- intensive care unit
- endothelial cells
- case report
- physical activity
- mycobacterium tuberculosis
- oxidative stress
- early onset
- low dose
- healthcare
- multiple sclerosis
- white matter
- atrial fibrillation
- resting state
- high dose
- brain injury
- tertiary care
- subarachnoid hemorrhage
- functional connectivity
- pulmonary tuberculosis
- cell free
- electronic health record
- peripheral nerve
- acinetobacter baumannii
- cerebral ischemia
- blood brain barrier
- adverse drug