Faster Aspart Versus Insulin Aspart as Part of a Basal-Bolus Regimen in Inadequately Controlled Type 2 Diabetes: The onset 2 Trial.

Keith BoweringChristopher CaseJohn HarveyMichael ReevesMichael SampsonRobert StrzinekDitte-Marie BretlerRikke Beck BangBruce W Bode

Published in: Diabetes care (2017)

Faster aspart and IAsp were confirmed noninferior in a basal-bolus regimen regarding change from baseline in HbA1c. Faster aspart improved 1-h PPG with no differences in 2-4-h PPG versus IAsp. Overall hypoglycemia rates were similar except for an increase in 0-2-h postmeal hypoglycemia with faster aspart.

Keyphrases

type diabetes
glycemic control
cardiovascular disease
clinical trial
phase ii
adipose tissue
placebo controlled