A pH-Responsive Drug-Delivery System Based on Apatinib-Loaded Metal-Organic Frameworks for Ferroptosis-Targeted Synergistic Anti-Tumor Therapy.

Fengyi YangQiaoyan DongZhuo ChenBenjian GaoDongning Zheng Rui WangShu QinFangyi PengMing LuoJin YangMengmei NieBo LiXiaoli Yang

Published in: International journal of nanomedicine (2024)

We have successfully constructed a MOF delivery system with excellent safety, sustained-release capability, pH-targeting, and improved anti-tumor efficacy, highlighting its potential as a therapeutic approach for the treatment of HCC.

Keyphrases

metal organic framework
cancer therapy
drug delivery
cell death
wastewater treatment
stem cells
replacement therapy
bone marrow
wound healing