Visual histological assessment of morphological features reflects the underlying molecular profile in invasive breast cancer: a morphomolecular study.
Emad A RakhaMansour AlsaleemKhloud A ElSharawyMichael S TossSara RaafatRaluca MihaiFayyaz A MinhasAndrew R GreenNasir M RajpootLeslie W DaltonNigel P MonganPublished in: Histopathology (2020)
Morphological features are probably related to distinct underlying molecular profiles that drive both morphology and behaviour. This study provides further evidence to support the use of image-based analysis of WSIs, including artificial intelligence algorithms, to predict tumour molecular profiles and outcome.