Women With a History of Preeclampsia Exhibit Accelerated Aging and Unfavorable Profiles of Senescence Markers.
Sonja SuvakovLisa E VaughanSantosh ParashuramYvonne Butler TobahMuthuvel JayachandranAndrea G KattahAlanna M ChamberlainSuzette J BielinskiNatasa MilicVesna D GarovicPublished in: Hypertension (Dallas, Tex. : 1979) (2024)
Our data suggest that a history of preeclampsia is associated with accelerated aging as indicated by senescence marker differences and the accumulation of multimorbidity later in life. Targeting cellular senescence may offer novel, mechanism-based approaches for the diagnosis and treatment of adverse health outcomes in women with a history of preeclampsia.