Cardiac hemodynamics in fetuses with transposition of the great arteries and intact ventricular septum from diagnosis to end of pregnancy: a longitudinal follow-up.

Compared to normal, fetuses with TGA-IVS undergo a complex redistribution of flow during the second half of the pregnancy with higher global pulmonary flow, lower ductal flow (with a negative diastolic flow at the end of pregnancy), and a smaller foramen ovale. In addition, fetal cardiac hemodynamic anomalies observed at 28-32 weeks of gestation were associated to lower postnatal tcSO2 . These observations may provide a better understanding of a premature closure of the foramen ovale and postnatal hypoxia that are specific to the physiology in TGA-IVS. This article is protected by copyright. All rights reserved.