Raising AWaRe-ness of antimicrobial stewardship challenges in pediatric emergency care: results from the PERFORM study assessing consistency and appropriateness of antibiotic prescribing across Europe.
Laura KolbergAakash KhanijauFabian Johannes Stanislaus van der VeldenJethro HerbergTisham DeRachel GalassiniAubrey J CunningtonVictoria J WrightPriyen ShahMyrsini KaforouClare WilsonTaco W KuijpersFederico M TorresIrene Rivero CalleHenriette A MollClementien VermontMarko PokornMojca KolnikAndrew J PollardPhilipp Kwame Abayie AgyemanLuregn J SchlapbachMaria N TsoliaShunmay YeungDace ZavadskaWerner ZenzNina A SchweintzgerMichiel van der FlierRonald de GrootEffua UsufMarie VoiceLeonides Calvo-BadoFrançois MalletKaty FidlerMichael LevinEnitan D CarrolMarieke EmontsUlrich von Bothnull nullPublished in: Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)
Differentiating bacterial from viral etiology in febrile illness on initial ED presentation remains challenging, resulting in a substantial over-prescription of antibiotics. A significant proportion of patients with a 'viral' phenotype received systemic antibiotics, predominantly classified as WHO Watch. Rapid and accurate point-of-care tests in the ED differentiating between bacterial and viral etiology, could significantly improve AMS.