Discovery and validation of tissue-specific DNA methylation as noninvasive diagnostic markers for colorectal cancer.

Dapeng LiLei ZhangJinming FuHao HuangYanlong LiuLin ZhuHongru SunSimin SunDing ZhangTian TianFan WangFulan HuXiaolin PengGairui LiLiyuan ZhaoTing ZhengXuan WangBinbin CuiYaShuang Zhao

Published in: Clinical epigenetics (2022)

Hypermethylation of the ten CpG sites is a CRC-specific alteration in tissue and has the potential use as a noninvasive cfDNA marker to diagnose CRC.

Keyphrases

dna methylation
genome wide
gene expression
small molecule
high throughput