Pharmacokinetic and pharmacodynamic equivalence of Biocon's biosimilar Insulin-R with the US-licensed Humulin® R formulation in healthy subjects: Results from the RHINE-1 (Recombinant Human INsulin Equivalence-1) study.
Leona Plum-MörschelGursharan SinghSundara Moorthi Nainar MurugesanAshwani MarwahJayanti PandaSubramanian LoganathanSandeep N AthalyePublished in: Diabetes, obesity & metabolism (2022)
PK and PD equivalence was demonstrated between Biocon's Insulin-R and Humulin-R in healthy subjects. Treatment with Biocon's Insulin-R and Humulin-R was well tolerated.